Publications

Published research, books and commentaries

2024

Interpretation and use of a decision support tool for multiple treatment options: a combined randomised controlled trial and survey of medical students

Stokke Hunskaar B, Løvsletten PO, Muller A, Vandvik PO.BMJ Evid Based Med. 2024 Jan 19;29(1):29-36. doi: 10.1136/bmjebm-2023-112370 View publication

Newborn and child health national and provincial clinical practice guidelines in South Africa, Nigeria and Malawi: a scoping review

Mthethwa M, Mbeye NM, Effa E, Arikpo D, Blose N, Brand A, Chibuzor M, Chipojola R, Durao S, Esu E, Kallon II, Kunje G, Lakudzala S, Naude C, Leong TD, Lewin S, Mabetha D, McCaul M, Meremikwu M, Vandvik PO, Kredo T.BMC Health Serv Res. 2024 Feb 19;24(1):221. doi: 10.1186/s12913-024-10682-0.PMID: 38374031 View publication

For which patients do the latest lipid lowering treatments reduce cardiovascular events?

Bardoczi JB, Rossen M, Eugster N, Agoritsas T, Gencer B, Rodondi N; Rev Med Suisse. 2024 Mar 6;20(864):472-479. French. doi: 10.53738/REVMED.2024.20.864.472 View publication

Interventions for the management of post COVID-19 condition (long COVID): Protocol for a living systematic review & network meta-analysis

Zeraatkar D, Ling M, Kirsh S, Jassal T; medRxiv, 2024.03. 15.24304168; DOI:10.1101/2024.03.15.24304168; View publication

Scraps of national clinical guidelines from the Directorate of Health

Helsingen LM, Langeland EA, Pisani SER, Vandvik PO, Haavardsholm EA, Malt UF, Müller C, Stensvold A, Kalager M, Bretthauer M.Tidsskr Nor Laegeforen. 2024 Mar 20;144(5). doi: 10.4045/tidsskr.24.0141. Print 2024 Apr 23.PMID: 38651715 View publication

Activity outcomes after hip arthroplasty: an information tool based on patients’ experience captured in a hospital registry

Fabiano G, Cole S, Barea C, Cullati S, Agoritsas T, Gutacker N, Silman A, Hannouche D, Lübbeke A, Pinedo-Villanueva R; BMC Musculoskelet Disord. 2024 Apr 1;25(1):255. doi: 10.1186/s12891-024-07357-6. View publication

Using a priority setting exercise to identify priorities for guidelines on newborn and child health in South Africa, Malawi, and Nigeria

Durão S, Effa E, Mbeye N, Mthethwa M, McCaul M, Naude C, Brand A, Blose N, Mabetha D, Chibuzor M, Arikpo D, Chipojola R, Kunje G, Vandvik PO, Esu E, Lewin S, Kredo T.Health Res Policy Syst. 2024 Apr 16;22(1):48. doi: 10.1186/s12961-024-01133-7 View publication

Which trial do we need? Randomized, placebo-controlled trial of antiviral treatment in patients hospitalized for influenza

Hosszu-Fellous K, Vetter P, Agoritsas T, Kaiser L; Clin Microbiol Infect. 2024 May;30(5):567-569. doi: 10.1016/j.cmi.2024.01.025 View publication

Patients’ experience on pain outcomes after hip arthroplasty: insights from an information tool based on registry data

Digital encounter decision aids linked to clinical practice guidelines: results from user testing SHARE-IT decision aids in primary care.

Van Bostraeten P, Aertgeerts B, Bekkering G, Delvaux N, Haers A, Vanheeswyck M, Vandekendelaere A, Van der Auwera N, Dijckmans C, Ostyn E, Soontjens W, Matthysen W, Schenk N, Mertens L, Jaeken J, Agoritsas T, Vermandere M. BMC Med Inform Decis Mak. 2023 May 22;23(1):97. doi: 10.1186/s12911-023-02186-4. PMID: 37217915 Free PMC article. View publication

Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials

Shi Q, Wang Y, Hao Q, Vandvik PO, Guyatt G, Li J, Chen Z, Xu S, Shen Y, Ge L, Sun F, Li L, Yu J, Nong K, Zou X, Zhu S, Wang C, Zhang S, Qiao Z, Jian Z, Li Y, Zhang X, Chen K, Qu F, Wu Y, He Y, Tian H, Li S.Lancet. 2024 Apr 6;403(10434):e21-e31. doi: 10.1016/S0140-6736(24)00351-9 View publication

Computer-Aided Diagnosis for Leaving Colorectal Polyps In Situ : A Systematic Review and Meta-analysis

Hassan C, Misawa M, Rizkala T, Mori Y, Sultan S, Facciorusso A, Antonelli G, Spadaccini M, Houwen BBSL, Rondonotti E, Patel H, Khalaf K, Li JW, Fernandez GM, Bhandari P, Dekker E, Gross S, Berzin T, Vandvik PO, Correale L, Kudo SE, Sharma P, Rex DK, Repici A, Foroutan F; CADx Analysis Study Group.Ann Intern Med. 2024 Jul;177(7):919-928. doi: 10.7326/M23-2865; View publication

Interventional treatments for chronic, axial or radicular, non-cancer, spinal pain: a protocol for a systematic review and network meta-analysis of randomised trials

X, Martin G, Sadeghirad B, Darzi AJ, Couban RJ, Florez ID, Crandon HN, Kum E, Chang Y, Esfahani MA, Sivananthan L, Mehrabi F, Sengupta NK, Rathod P, Morsi RZ, Buckley DN, Guyatt GH, Rampersaud YR, Standaert CJ, Agoritsas T, Busse JW; BMJ Open. 2021 Jul 9;11(7):e046025. doi: 10.1136/bmjopen-2020-046025 View publication

Physicians found an interactive tool displaying structured evidence summaries for multiple comparisons understandable and useful: a qualitative user testing study

Løvsletten PO, Hunskaar BS, Heen AF, Bekkering G, Poel LV, Zeraatkar D, Vermandere M, Aertgeerts B, Delvaux N, Achille F, Busse JW, Agoritsas T, Vandvik PO; J Clin Epidemiol. 2024 Aug;172:111399. doi: 10.1016/j.jclinepi.2024.111399. View publication

Evaluating the impact of the global evidence, local adaptation (GELA) project for enhancing evidence-informed guideline recommendations for newborn and young child health in three African countries: a mixed-methods protocol

Kredo T, Effa E, Mbeye N, Mabetha D, Schmidt BM, Rohwer A, McCaul M, Kallon II, Munabi-Babigumira S, Glenton C, Young T, Lewin S, Vandvik PO, Cooper S.Health Res Policy Syst. 2024 Aug 19;22(1):114. doi: 10.1186/s12961-024-01189-5.PMID: 39160559 View publication

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors for adults with chronic kidney disease: a clinical practice guideline

Agarwal A, Zeng X, Li S, Rayner D, Foroutan F, Aertgeerts B, Coyac F, Darbellay Farhoumand P, Demaine A, Heen A, Jha V, Machuve E, Nagler E, Tunnicliffe D, Guyatt G, Vandvik P, Ponte B, Agoritsas T; British Medical Journal Publishing Group. 2024; 387 doi: https://doi.org/10.1136/bmj-2024-080257 View publication

Proactive therapeutic drug monitoring of biologic drugs in adult patients with inflammatory bowel disease, inflammatory arthritis, or psoriasis: a clinical practice guideline

Kawano-Dourado L, Kristianslund EK, Zeraatkar D, Jani M, Makharia G, Hazlewood G, Smith C, Jess T, Stabell C,Schatten A, Owen A, Gehin J, Katsidzira L, Weinberg D, Bauer-Ventura I, Tugwell P, Moayyedi P, Wolff Cecchi AV, Shimabuco A, Seterelv S, Gyuatt G, Agoritsas T, Vandvik PO; BMJ 2024;387:e079830; doi: https://doi.org/10.1136/bmj-2024-079830 View publication

A systematic survey of 200 systematic reviews with network meta-analysis (published 2020–2021) reveals that few reviews report structured evidence summaries

Løvsletten PO, Wang X, Pitre T, Ødegaard M, Angeliki AV, Lunny C, Tricco AC, Agoritsas T, Vandvik PO; Journal of Clinical Epidemiology,Volume 173, 2024; https://doi.org/10.1016/j.jclinepi.2024.111445 View publication

MATCH-IT: A decision support tool for multiple comparisons presenting data from network meta-analysis to facilitate guideline development

Hunskaar BS, Løvsletten P, Achille F, Heen A, Agoritsas T, Vandvik P; Clinical and Public Health Guidelines: Volume 1, Issue 4, 2024; https://doi.org/10.1002/gin2.70003 View publication

Prospective Registration of Trials: Where we are, why, and how we could get better

Mongin D, Buitrago-Garcia, D, Capderou S, Agoritsas T, Gabay C, Courvoisier DS, Iudici M; J Clin Epidemiol. 2024 Oct 29:111586. doi: 10.1016/j.jclinepi.2024.111586. View publication

Computer-aided diagnosis for the resect-and-discard strategy for colorectal polyps: a systematic review and meta-analysis

Hassan C, Rizkala T, Mori Y, Spadaccini M, Misawa M, Antonelli G, Rondonotti E, Dekker E, Houwen BBSL, Pech O, Baumer S, Li JW, von Renteln D, Haumesser C, Maselli R, Facciorusso A, Correale L, Menini M, Schilirò A, Khalaf K, Patel H, Radadiya DK, Bhandari P, Kudo SE, Sultan S, Vandvik PO, Sharma P, Rex DK, Foroutan F, Repici A; CADx analysis study group.Lancet Gastroenterol Hepatol. 2024 Nov;9(11):1010-1019. doi: 10.1016/S2468-1253(24)00222

How to best convey continuous outcomes in patient decision aids

Glyn Elwyn G, Durand MA, Agoritsas T, Mayer M; BMJ Evidence-Based Medicine; 2024. doi: 10.1136/bmjebm-2024-112871 View publication

2023

Digital encounter decision aids linked to clinical practice guidelines: results from user testing SHARE-IT decision aids in primary care.

Qualitative study of guideline panelists: innovative surveys provided valuable insights regarding patient values and preferences.

Zeng L, Li SA, Yang M, Yan L, Helsingen LM, Bretthauer M, Agoritsas T, Vandvik PO, Mustafa RA, Busse J, Siemieniuk RAC, Lytvyn L, Zhang L, Brignardello-Petersen R, Guyatt GH. J Clin Epidemiol. 2023 Sep;161:173-180. doi: 10.1016/j.jclinepi.2023.07.014. Epub 2023 Jul 29. PMID: 37517505 View publication

Management of chronic pain secondary to temporomandibular disorders: a systematic review and network meta-analysis of randomised trials.

Yao L, Sadeghirad B, Li M, Li J, Wang Q, Crandon HN, Martin G, Morgan R, Florez ID, Hunskaar BS, Wells J, Moradi S, Zhu Y, Ahmed MM, Gao Y, Cao L, Yang K, Tian J, Li J, Zhong L, Couban RJ, Guyatt GH, Agoritsas T, Busse JW. BMJ. 2023 Dec 15;383:e076226. doi: 10.1136/bmj-2023-076226. PMID: 38101924 View publication

Interpretation and use of a decision support tool for multiple treatment options: a combined randomised controlled trial and survey of medical students

Stokke Hunskaar B, Løvsletten PO, Muller A, et al. BMJ Evidence-Based Medicine. Published First: 13October, http://orcid.org/0000-0002-3340-0591 View publication

Regarding Treatment of Atopic Dermatitis (Eczema): A Systematic Review.

Maleki-Yazdi KA, Heen AF, Zhao IX, et al. Values and Preferences of Patients and Caregivers JAMA Dermatol. 2023;159(3):320–330 doi:10.1001/jamadermatol.2022.6045 View publication

Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.

Shi Q, Nong K, Vandvik PO, Guyatt GH, Schnell O, Rydén L, Marx N, Brosius FC 3rd, Mustafa RA, Agarwal A, Zou X, Mao Y, Asadollahifar A, Chowdhury SR, Zhai C, Gupta S, Gao Y, Lima JP, Numata K, Qiao Z, Fan Q, Yang Q, Jin Y, Ge L, Yang Q, Zhu H, Yang F, Chen Z, Lu X, He S, Chen X, Lyu X, An X, Chen Y, Hao Q, Standl E, Siemieniuk R, Agoritsas T, Tian H, Li S. BMJ. 2023 Apr 6;381:e074068. doi: 10.1136/bmj-2022-074068. PMID: 37024129; PMCID: PMC10077111.  View publication

Response with Trial-reported Analyses of Binary Subgroups

Li S, Litvin V, Manski CF. Partial Identification of Personalized Treatment. Epidemiology. 2023 May 1;34(3):319-324. Epub 2023 Jan 30. PMID: 36715981. doi: 10.1097/EDE.0000000000001593.  View publication

Preventive care recommendations to promote health equity

Persaud N, Sabir A, Woods H, Sayani A, Agarwal A, Chowdhury M, de Leon-Demare K, Ibezi S, Jan SH, Katz A, LaFortune FD, Lewis M, McFarlane T, Oberai A, Oladele Y, Onyekwelu O, Peters L, Wong P, Lofters A; Equitable Preventive Praxis Initiative in Canada.CMAJ. 2023 Sep 25;195(37):E1250-E1273. doi: 10.1503/cmaj.230237.PMID: 37748784 View publication

Canadian Rheumatology Association Living Guidelines for Rheumatoid Arthritis: Update #1

Hazlewood GS, Akhavan P, Pardo JP, Agarwal A, Schieir O, Barber CEH, Proulx L, Richards DP, Bombardier C, Pope JE, Barnabe C, Tugwell P, Jamal S, Thorne JC, Nikolic RPA, Khraishi M, Bansback N, Legge A, Bykerk V, Taylor-Gjevre R.J Rheumatol. 2023 Sep;50(9):1198-1199. doi: 10.3899/jrheum.2023-0625. Epub 2023 Aug 1.PMID: 37527865 View publication

New-onset atrial fibrillation in critically ill adult patients-an SSAI clinical practice guideline

Andreasen AS, Wetterslev M, Sigurdsson MI, Bove J, Kjaergaard J, Aslam TN, Järvelä K, Poulsen M, De Geer L, Agarwal A, Kjaer MN, Møller MH.Acta Anaesthesiol Scand. 2023 Sep;67(8):1110-1117. doi: 10.1111/aas.14262. Epub 2023 May 24.PMID: 37289426 View publication

Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials

Shi Q, Nong K, Vandvik PO, Guyatt GH, Schnell O, Rydén L, Marx N, Brosius FC 3rd, Mustafa RA, Agarwal A, Zou X, Mao Y, Asadollahifar A, Chowdhury SR, Zhai C, Gupta S, Gao Y, Lima JP, Numata K, Qiao Z, Fan Q, Yang Q, Jin Y, Ge L, Yang Q, Zhu H, Yang F, Chen Z, Lu X, He S, Chen X, Lyu X, An X, Chen Y, Hao Q, Standl E, Siemieniuk R, Agoritsas T, Tian H, Li S.BMJ. 2023 Apr 6;381:e074068. doi: 10.1136/bmj-2022-074068.PMID: 37024129 View publication

Management of chronic pain associated with temporomandibular disorders: a clinical practice guideline.

Busse JW, Casassus R, Carrasco-Labra A, Durham J, Mock D, Zakrzewska JM, Palmer C, Samer CF, Coen M, Guevremont B, Hoppe T, Guyatt GH, Crandon HN, Yao L, Sadeghirad B, Vandvik PO, Siemieniuk RAC, Lytvyn L, Hunskaar BS, Agoritsas T. BMJ. 2023 Dec 15;383:e076227. doi: 10.1136/bmj-2023-076227.PMID: 38101929 View publication

Infographic summaries for clinical practice guidelines: results from user testing of the BMJ Rapid Recommendations in primary care.

Van Bostraeten P, Aertgeerts B, Bekkering GE, Delvaux N, Dijckmans C, Ostyn E, Soontjens W, Matthysen W, Haers A, Vanheeswyck M, Vandekendelaere A, Van der Auwera N, Schenk N, Stahl-Timmins W, Agoritsas T, Vermandere M. BMJ Open. 2023 Nov 9;13(11):e071847. doi: 10.1136/bmjopen-2023-071847. PMID: 37945307 Free PMC article.

A novel framework for incorporating patient values and preferences in making guideline recommendations: guideline panel surveys.

Zeng L, Helsingen LM, Bretthauer M, Agoritsas T, Vandvik PO, Mustafa RA, Busse J, Siemieniuk RAC, Lytvyn L, Li SA, Yang M, Yan L, Zhang L, Brignardello-Petersen R, Guyatt GH. J Clin Epidemiol. 2023 Sep;161:164-172. doi: 10.1016/j.jclinepi.2023.07.003. Epub 2023 Jul 13. PMID: 37453455 View publication

Benefits and harms of drug treatment for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.

2022

UEG and EAES rapid guideline: Systematic review, meta-analysis, GRADE assessment and evidence-informed European recommendations on TaTME for rectal cancer

Milone M, Adamina M, Arezzo A, Bejinariu N, Boni L, Bouvy N, de Lacy FB, Dresen R, Ferentinos K, Francis NK, Mahaffey J, Penna M, Theodoropoulos G, Kontouli KM, Mavridis D, Vandvik PO, Antoniou SA. Surg Endosc. 2022 Feb 25. doi: 10.1007/s00464-022-09090-4. Online ahead of print. PMID: 35212821 View publication

EAES rapid guideline: systematic review, network meta-analysis, CINeMA and GRADE assessment, and European consensus on bariatric surgery-extension 2022

Carrano FM, Iossa A, Di Lorenzo N, Silecchia G, Kontouli KM, Mavridis D, Alarçon I, Felsenreich DM, Sanchez-Cordero S, Di Vincenzo A, Balagué-Ponz MC, Batterham RL, Bouvy N, Copaescu C, Dicker D, Fried M, Godoroja D, Goitein D, Halford JCG, Kalogridaki M, De Luca M, Morales-Conde S, Prager G, Pucci A, Vilallonga R, Zani I, Vandvik PO, Antoniou SA; EAES Bariatric Surgery Guidelines Group. Surg Endosc. 2022 Mar;36(3):1709-1725. doi: 10.1007/s00464-022-09008-0. Epub 2022 Jan 20. PMID: 35059839 View publication

Decision makers need constantly updated evidence synthesis

Elliott J, Lawrence R, Minx JC, Oladapo OT, Ravaud P, Tendal Jeppesen B, Thomas J, Turner T, Vandvik PO, Grimshaw JM. Nature. 2021 Dec;600(7889):383-385. doi: 10.1038/d41586-021-03690-1. PMID: 34912079 No abstract available. View publication

Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials

Shi Q, Wang Y, Hao Q, Vandvik PO, Guyatt G, Li J, Chen Z, Xu S, Shen Y, Ge L, Sun F, Li L, Yu J, Nong K, Zou X, Zhu S, Wang C, Zhang S, Qiao Z, Jian Z, Li Y, Zhang X, Chen K, Qu F, Wu Y, He Y, Tian H, Li S. Lancet. 2022 Jan 15;399(10321):259-269. doi: 10.1016/S0140-6736(21)01640-8. Epub 2021 Dec 8. PMID: 34895470 View publication

Direct Oral Anticoagulants Compared With Dalteparin for Treatment of Cancer-Associated Thrombosis: A Living, Interactive Systematic Review and Network Meta-analysis.

Riaz IB, Fuentes HE, Naqvi SAA, He H, Sipra QR, Tafur AJ, Padranos L, Wysokinski WE, Marshall AL, Vandvik PO, Montori V, Bryce AH, Liu H, Badgett RG, Murad MH, McBane RD 2nd. Mayo Clin Proc. 2022 Feb;97(2):308-324. doi: 10.1016/j.mayocp.2020.10.041. Epub 2021 Jun 22. PMID: 341722909. View publication

2021

Values, preferences and burden of treatment for the initiation of GLP-1 receptor agonists and SGLT-2 inhibitors in adult patients with type 2 diabetes: a systematic review

González-González JG, Díaz González-Colmenero A, Millán-Alanís JM, Lytvyn L, Solis RC, Mustafa RA, Palmer SC, Li S, Hao Q, Alvarez-Villalobos NA, Vandvik PO, Rodríguez-Gutiérrez R. BMJ Open. 2021 Jul 9;11(7):e049130. doi: 10.1136/bmjopen-2021-049130. PMID: 34244276 Free PMC article. View publication

COVID-19: living guidelines help fix cracks in evidence pipeline.

Vandvik PO, Askie L, Glen F, Tendal B, Agoritsas T. Nature. 2021 Jul;595(7866):172. doi: 10.1038/d41586-021-01821-2. PMID: 34230655 No abstract available. View publication

Decision aids linked to evidence summaries and clinical practice guidelines: results from user-testing in clinical encounters.

Heen AF, Vandvik PO, Brandt L, Achille F, Guyatt GH, Akl EA, Treewek S, Agoritsas T. BMC Med Inform Decis Mak. 2021 Jun 29;21(1):202. doi: 10.1186/s12911-021-01541-7. PMID: 34187484 Free PMC article. View publication

Towards living guidelines on cardiorenal outcomes in diabetes: A pilot project of the Taskforce of the Guideline Workshop 2020.

Marx N, Ryden L, Brosius F, Ceriello A, Cheung M, Cosentino F, Green J, Kellerer M, Koob S, Kosiborod M, Prashant Nedungadi T, Rodbard HW, Vandvik PO, Ji L, Sheu WH, Standl E, Schnell O. Diabetes Res Clin Pract. 2021 Jul;177:108870. doi: 10.1016/j.diabres.2021.108870. Epub 2021 May 24. PMID: 34044026 Review. View publication

EAES rapid guideline: appendicitis in the elderly.

Antoniou SA, Mavridis D, Kontouli KM, Drakopoulos V, Gorter-Stam M, Eriksson S, Leone M, Pérez-Bocanegra MC, Smart NJ, Milone M, Carrano FM, Antoniou GA, Vandvik PO. Surg Endosc. 2021 Jul;35(7):3233-3243. doi: 10.1007/s00464-021-08524-9. Epub 2021 May 17. PMID: 33999255 View publication

SGLT-2 inhibitors or GLP-1 receptor agonists for adults with type 2 diabetes: a clinical practice guideline.

Li S, Vandvik PO, Lytvyn L, Guyatt GH, Palmer SC, Rodriguez-Gutierrez R, Foroutan F, Agoritsas T, Siemieniuk RAC, Walsh M, Frere L, Tunnicliffe DJ, Nagler EV, Manja V, Åsvold BO, Jha V, Vermandere M, Gariani K, Zhao Q, Ren Y, Cartwright EJ, Gee P, Wickes A, Ferns L, Wright R, Li L, Hao Q, Mustafa RA. BMJ. 2021 May 11;373:n1091. doi: 10.1136/bmj.n1091. PMID: 33975892 View publication

Predictive models for cardiovascular and kidney outcomes in patients with type 2 diabetes: systematic review and meta-analyses.

Buchan TA, Malik A, Chan C, Chambers J, Suk Y, Zhu JW, Ge FZ, Huang LM, Vargas LA, Hao Q, Li S, Mustafa RA, Vandvik PO, Guyatt G, Foroutan F. Heart. 2021 Dec;107(24):1962-1973. doi: 10.1136/heartjnl-2021-319243. Epub 2021 Apr 8. PMID: 33833070 View publication

A Living, Interactive Systematic Review and Network Meta-analysis of First-line Treatment of Metastatic Renal Cell Carcinoma.

Riaz IB, He H, Ryu AJ, Siddiqi R, Naqvi SAA, Yao Y, Husnain M, Narasimhulu DM, Mathew J, Sipra QUAR, Vandvik PO, Joseph RW, Liu H, Wang Z, Herasevich V, Singh P, Hussain SA, Ho TH, Bryce AH, Pagliaro LC, Murad MH, Costello BA. Eur Urol. 2021 Dec;80(6):712-723. doi: 10.1016/j.eururo.2021.03.016. Epub 2021 Apr 3. PMID: 33824031 Review. View publication

A living WHO guideline on drugs to prevent covid-19.

Lamontagne F, Agoritsas T, Siemieniuk R, Rochwerg B, Bartoszko J, Askie L, Macdonald H, Amin W, Bausch FJ, Burhan E, Cecconi M, Chanda D, Dat VQ, Du B, Geduld H, Gee P, Nerina H, Hashimi M, Hunt BJ, Kabra S, Kanda S, Kawano-Dourado L, Kim YJ, Kissoon N, Kwizera A, Leo YS, Mahaka I, Manai H, Mino G, Nsutebu E, Pshenichnaya N, Qadir N, Ranganathan SS, Sabzwari S, Sarin R, Sharland M, Shen Y, Souza JP, Stegemann M, Ugarte S, Venkatapuram S, Vuyiseka D, Preller J, Brignardello-Petersen R, Kum E, Qasim A, Zeraatkar D, Owen A, Guyatt G, Lytvyn L, Diaz J, Vandvik PO, Jacobs M. BMJ. 2021 Mar 1;372:n526. doi: 10.1136/bmj.n526. PMID: 33649077 View publication

Patient values and preferences on valve replacement for aortic stenosis: a systematic review.

Heen AF, Lytvyn L, Shapiro M, Guyatt GH, Siemieniuk RAC, Zhang Y, Manja V, Vandvik PO, Agoritsas T. Heart. 2021 Aug;107(16):1289-1295. doi: 10.1136/heartjnl-2020-318334. Epub 2021 Feb 9. PMID: 33563630 Free PMC article. View publication

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network meta-analysis of randomised controlled trials.

Palmer SC, Tendal B, Mustafa RA, Vandvik PO, Li S, Hao Q, Tunnicliffe D, Ruospo M, Natale P, Saglimbene V, Nicolucci A, Johnson DW, Tonelli M, Rossi MC, Badve SV, Cho Y, Nadeau-Fredette AC, Burke M, Faruque LI, Lloyd A, Ahmad N, Liu Y, Tiv S, Millard T, Gagliardi L, Kolanu N, Barmanray RD, McMorrow R, Raygoza Cortez AK, White H, Chen X, Zhou X, Liu J, Rodríguez AF, González-Colmenero AD, Wang Y, Li L, Sutanto S, Solis RC, Díaz González-Colmenero F, Rodriguez-Gutierrez R, Walsh M, Guyatt G, Strippoli GFM. BMJ. 2021 Jan 13;372:m4573. doi: 10.1136/bmj.m4573. PMID: 33441402 Free PMC article. View publication

2020

Establishing thresholds for important benefits considering the harms of screening interventions.

Helsingen LM, Zeng L, Siemieniuk RA, Lytvyn L, Vandvik PO, Agoritsas T, Bretthauer M, Guyatt G. BMJ Open. 2020 Dec 2;10(12):e037854. doi: 10.1136/bmjopen-2020-037854. PMID: 33268400 Free PMC article. View publication

A framework for practical issues was developed to inform shared decision-making tools and clinical guidelines.

Heen AF, Vandvik PO, Brandt L, Montori VM, Lytvyn L, Guyatt G, Quinlan C, Agoritsas T. J Clin Epidemiol. 2021 Jan;129:104-113. doi: 10.1016/j.jclinepi.2020.10.002. Epub 2020 Oct 10. PMID: 33049326 View publication

Developing Guidelines Before, During, and After the COVID-19 Pandemic.

Munn Z, Twaddle S, Service D, Harrow E, Okwen PM, Schünemann H, Vandvik PO. Ann Intern Med. 2020 Dec 15;173(12):1012-1014. doi: 10.7326/M20-4907. Epub 2020 Sep 15. PMID: 32931327 Free PMC article. View publication

Proceedings of the Guideline Workshop 2019: Strategies for the Optimization of Guideline Processes in Diabetes, Cardiovascular Diseases, and Kidney Diseases.

Marx N, Rydén L, Brosius F, Ceriello A, Cheung M, Cosentino F, Green J, Kellerer M, Koob S, Kosiborod M, Nedungadi P, Rodbard HW, Vandvik PO, Standl E, Schnell O. Diabetes Technol Ther. 2020 Jul;22(7):546-552. doi: 10.1089/dia.2020.0086. Epub 2020 Jun 26. PMID: 32903066 View publication

A living WHO guideline on drugs for covid-19.

Agarwal A, Rochwerg B, Lamontagne F, Siemieniuk RA, Agoritsas T, Askie L, Lytvyn L, Leo YS, Macdonald H, Zeng L, Amin W, Barragan FAJ, Bausch FJ, Burhan E, Calfee CS, Cecconi M, Chanda D, Dat VQ, De Sutter A, Du B, Geduld H, Gee P, Gotte M, Harley N, Hashimi M, Hunt B, Jehan F, Kabra SK, Kanda S, Kim YJ, Kissoon N, Krishna S, Kuppalli K, Kwizera A, Lisboa T, Mahaka I, Manai H, Mino G, Nsutebu E, Preller J, Pshenichnaya N, Qadir N, Sabzwari S, Sarin R, Shankar-Hari M, Sharland M, Shen Y, Ranganathan SS, Souza JP, Stegemann M, Swanstrom R, Ugarte S, Venkatapuram S, Vuyiseka D, Wijewickrama A, Maguire B, Tran L, Zeraatkar D, Bartoszko JJ, Ge L, Brignardello-Petersen R, Owen A, Guyatt G, Diaz J, Kawano-Dourado L, Jacobs M, Vandvik PO. BMJ. 2020 Sep 4;370:m3379. doi: 10.1136/bmj.m3379. PMID: 32887691 Updated. View publication

Remdesivir for severe covid-19: a clinical practice guideline.

Rochwerg B, Agarwal A, Zeng L, Leo YS, Appiah JA, Agoritsas T, Bartoszko J, Brignardello-Petersen R, Ergan B, Ge L, Geduld H, Gershengorn HB, Manai H, Huang M, Lamontagne F, Kanda S, Kawano-Dourado L, Kurian L, Kwizera A, Murthy S, Qadir N, Siemieniuk R, Silvestre MA, Vandvik PO, Ye Z, Zeraatkar D, Guyatt G. BMJ. 2020 Jul 30;370:m2924. doi: 10.1136/bmj.m2924. PMID: 32732352 View publication

The future of colorectal cancer screening: Parentalism or shared decision-making?

Bretthauer M, Helsingen LM, Kalager M, Vandvik PO, Agoritsas T, Guyatt G. CMAJ. 2020 May 4;192(18):E484. doi: 10.1503/cmaj.74839. PMID: 32366471 Free PMC article. No abstract available. View publication

Future of Evidence Ecosystem Series: Evidence ecosystems and learning health systems: why bother?

Vandvik PO, Brandt L. J Clin Epidemiol. 2020 Jul;123:166-170. doi: 10.1016/j.jclinepi.2020.02.008. Epub 2020 Mar 4. PMID: 32145365 No abstract available. View publication

Proceedings of the Guideline Workshop 2019 - Strategies for the optimization of guideline processes in diabetes, cardiovascular diseases and kidney diseases.

Marx N, Rydén L, Brosius F, Ceriello A, Cheung M, Cosentino F, Green J, Kellerer M, Koob S, Kosiborod M, Nedungadi P, Rodbard HW, Vandvik PO, Standl E, Schnell O. Diabetes Res Clin Pract. 2020 Apr;162:108092. doi: 10.1016/j.diabres.2020.108092. Epub 2020 Feb 26. PMID: 32109519 View publication

GRADE Guidelines 28: Use of GRADE for the assessment of evidence about prognostic factors: rating certainty in identification of groups of patients with different absolute risks.

Foroutan F, Guyatt G, Zuk V, Vandvik PO, Alba AC, Mustafa R, Vernooij R, Arevalo-Rodriguez I, Munn Z, Roshanov P, Riley R, Schandelmaier S, Kuijpers T, Siemieniuk R, Canelo-Aybar C, Schunemann H, Iorio A. J Clin Epidemiol. 2020 May;121:62-70. doi: 10.1016/j.jclinepi.2019.12.023. Epub 2020 Jan 23. PMID: 31982539 View publication

Gastrointestinal bleeding prophylaxis for critically ill patients: a clinical practice guideline.

Ye Z, Reintam Blaser A, Lytvyn L, Wang Y, Guyatt GH, Mikita JS, Roberts J, Agoritsas T, Bertschy S, Boroli F, Camsooksai J, Du B, Heen AF, Lu J, Mella JM, Vandvik PO, Wise R, Zheng Y, Liu L, Siemieniuk RAC. BMJ. 2020 Jan 6;368:l6722. doi: 10.1136/bmj.l6722. PMID: 31907223 View publication

Efficacy and safety of gastrointestinal bleeding prophylaxis in critically ill patients: systematic review and network meta-analysis.

Wang Y, Ye Z, Ge L, Siemieniuk RAC, Wang X, Wang Y, Hou L, Ma Z, Agoritsas T, Vandvik PO, Perner A, Møller MH, Guyatt GH, Liu L. BMJ. 2020 Jan 6;368:l6744. doi: 10.1136/bmj.l6744. PMID: 31907166 Free PMC article. View publication

Subacromial decompression surgery for adults with shoulder pain: a systematic review with meta-analysis.

Lähdeoja T, Karjalainen T, Jokihaara J, Salamh P, Kavaja L, Agarwal A, Winters M, Buchbinder R, Guyatt G, Vandvik PO, Ardern CL. Br J Sports Med. 2020 Jun;54(11):665-673. doi: 10.1136/bjsports-2018-100486. Epub 2019 Jan 15. PMID: 30647053 View publication

2019

Pathways to independence: towards producing and using trustworthy evidence.

Moynihan R, Bero L, Hill S, Johansson M, Lexchin J, Macdonald H, Mintzes B, Pearson C, Rodwin MA, Stavdal A, Stegenga J, Thombs BD, Thornton H, Vandvik PO, Wieseler B, Godlee F. BMJ. 2019 Dec 3;367:l6576. doi: 10.1136/bmj.l6576. PMID: 31796508 No abstract available. View publication

[Colorectal cancer screening, yes or no?].

Helsingen LM, Vandvik PO, Jodal HC, Murphy SB, Heen AF, Kalager M, Bretthauer M. Tidsskr Nor Laegeforen. 2019 Oct 3;139(15). doi: 10.4045/tidsskr.19.0323. Print 2019 Oct 22. PMID: 31642636 Norwegian. No abstract available. View publication

Colorectal cancer screening with faecal testing, sigmoidoscopy or colonoscopy: a systematic review and network meta-analysis.

Jodal HC, Helsingen LM, Anderson JC, Lytvyn L, Vandvik PO, Emilsson L. BMJ Open. 2019 Oct 2;9(10):e032773. doi: 10.1136/bmjopen-2019-032773. PMID: 31578199 Free PMC article. View publication

Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a clinical practice guideline.

Helsingen LM, Vandvik PO, Jodal HC, Agoritsas T, Lytvyn L, Anderson JC, Auer R, Murphy SB, Almadi MA, Corley DA, Quinlan C, Fuchs JM, McKinnon A, Qaseem A, Heen AF, Siemieniuk RAC, Kalager M, Usher-Smith JA, Lansdorp-Vogelaar I, Bretthauer M, Guyatt G. BMJ. 2019 Oct 2;367:l5515. doi: 10.1136/bmj.l5515. PMID: 31578196 View publication

Colorectal cancer screening with faecal immunochemical testing, sigmoidoscopy or colonoscopy: a microsimulation modelling study.

Buskermolen M, Cenin DR, Helsingen LM, Guyatt G, Vandvik PO, Haug U, Bretthauer M, Lansdorp-Vogelaar I. BMJ. 2019 Oct 2;367:l5383. doi: 10.1136/bmj.l5383. PMID: 31578177 Free PMC article. View publication

Proprotein convertase subtilisin/kexin 9 inhibitors in reducing cardiovascular outcomes: a systematic review and meta-analysis.

Du H, Li X, Su N, Li L, Hao X, Gao H, Kwong JS, Vandvik PO, Yang X, Nemeth I, Mordi IR, Li Q, Zhang L, Rao L, Lang CC, Li J, Tian H, Li S. Heart. 2019 Aug;105(15):1149-1159. doi: 10.1136/heartjnl-2019-314763. Epub 2019 Mar 6. PMID: 30842207 View publication

Minimal important differences for improvement in shoulder condition patient-reported outcomes: a systematic review to inform a BMJRapid Recommendation.

Hao Q, Devji T, Zeraatkar D, Wang Y, Qasim A, Siemieniuk RAC, Vandvik PO, Lähdeoja T, Carrasco-Labra A, Agoritsas T, Guyatt G. BMJ Open. 2019 Feb 20;9(2):e028777. doi: 10.1136/bmjopen-2018-028777. PMID: 30787096 Free PMC article. View publication

Subacromial decompression surgery for adults with shoulder pain: a clinical practice guideline.

Vandvik PO, Lähdeoja T, Ardern C, Buchbinder R, Moro J, Brox JI, Burgers J, Hao Q, Karjalainen T, van den Bekerom M, Noorduyn J, Lytvyn L, Siemieniuk RAC, Albin A, Shunjie SC, Fisch F, Proulx L, Guyatt G, Agoritsas T, Poolman RW. BMJ. 2019 Feb 6;364:l294. doi: 10.1136/bmj.l294. PMID: 30728120 View publication

[The BMJ Rapid Recommendations: towards a new model for the production of clinical practice guidelines].

Agoritsas T, Darbellay Farhoumand P, Siemieniuk R, Heen AF, Lytvyn L, MacDonald H, Stahl-Timmins W, Guyatt G, Vandvik PO. Rev Med Suisse. 2019 Jan 9;15(N° 632-633):149-155. PMID: 30657266 French. View publication

2018

Dual antiplatelet therapy with aspirin and clopidogrel for acute high risk transient ischaemic attack and minor ischaemic stroke: a clinical practice guideline.

Prasad K, Siemieniuk R, Hao Q, Guyatt G, O'Donnell M, Lytvyn L, Heen AF, Agoritsas T, Vandvik PO, Gorthi SP, Fisch L, Jusufovic M, Muller J, Booth B, Horton E, Fraiz A, Siemieniuk J, Fobuzi AC, Katragunta N, Rochwerg B. BMJ. 2018 Dec 18;363:k5130. doi: 10.1136/bmj.k5130. PMID: 30563885 View publication

Opioids for Chronic Noncancer Pain: A Systematic Review and Meta-analysis.

Busse JW, Wang L, Kamaleldin M, Craigie S, Riva JJ, Montoya L, Mulla SM, Lopes LC, Vogel N, Chen E, Kirmayr K, De Oliveira K, Olivieri L, Kaushal A, Chaparro LE, Oyberman I, Agarwal A, Couban R, Tsoi L, Lam T, Vandvik PO, Hsu S, Bala MM, Schandelmaier S, Scheidecker A, Ebrahim S, Ashoorion V, Rehman Y, Hong PJ, Ross S, Johnston BC, Kunz R, Sun X, Buckley N, Sessler DI, Guyatt GH. JAMA. 2018 Dec 18;320(23):2448-2460. doi: 10.1001/jama.2018.18472. PMID: 30561481 Free PMC article. View publication

Including practical issues and patient perspectives in Rapid Recommendations.

Heen AF, Vandvik PO, Agoritsas T; MAGIC research and innovation programme. BMJ. 2018 Nov 20;363:k4871. doi: 10.1136/bmj.k4871. PMID: 30459184 No abstract available. View publication

Prostate cancer screening with prostate-specific antigen (PSA) test: a clinical practice guideline.

Tikkinen KAO, Dahm P, Lytvyn L, Heen AF, Vernooij RWM, Siemieniuk RAC, Wheeler R, Vaughan B, Fobuzi AC, Blanker MH, Junod N, Sommer J, Stirnemann J, Yoshimura M, Auer R, MacDonald H, Guyatt G, Vandvik PO, Agoritsas T. BMJ. 2018 Sep 5;362:k3581. doi: 10.1136/bmj.k3581. PMID: 30185545 Free PMC article. No abstract available. View publication

A systematic review of trials evaluating success factors of interventions with computerised clinical decision support.

Van de Velde S, Heselmans A, Delvaux N, Brandt L, Marco-Ruiz L, Spitaels D, Cloetens H, Kortteisto T, Roshanov P, Kunnamo I, Aertgeerts B, Vandvik PO, Flottorp S. Implement Sci. 2018 Aug 20;13(1):114. doi: 10.1186/s13012-018-0790-1. PMID: 30126421 Free PMC article. View publication

Understanding conflicts of interest.

Vandvik PO, Alhazzani W, Møller MH. Intensive Care Med. 2018 Oct;44(10):1738-1740. doi: 10.1007/s00134-018-5338-y. Epub 2018 Aug 6. PMID: 30083991 No abstract available. View publication

Corticosteroids in Sepsis: An Updated Systematic Review and Meta-Analysis.

Rochwerg B, Oczkowski SJ, Siemieniuk RAC, Agoritsas T, Belley-Cote E, D'Aragon F, Duan E, English S, Gossack-Keenan K, Alghuroba M, Szczeklik W, Menon K, Alhazzani W, Sevransky J, Vandvik PO, Annane D, Guyatt G. Crit Care Med. 2018 Sep;46(9):1411-1420. doi: 10.1097/CCM.0000000000003262. PMID: 29979221 View publication

The GUIDES checklist: development of a tool to improve the successful use of guideline-based computerised clinical decision support.

Van de Velde S, Kunnamo I, Roshanov P, Kortteisto T, Aertgeerts B, Vandvik PO, Flottorp S; GUIDES expert panel. Implement Sci. 2018 Jun 25;13(1):86. doi: 10.1186/s13012-018-0772-3. PMID: 29941007 Free PMC article. View publication

Development of a Tailored Intervention With Computerized Clinical Decision Support to Improve Quality of Care for Patients With Knee Osteoarthritis: Multi-Method Study.

Van de Velde S, Kortteisto T, Spitaels D, Jamtvedt G, Roshanov P, Kunnamo I, Aertgeerts B, Vandvik PO, Flottorp S. JMIR Res Protoc. 2018 Jun 11;7(6):e154. doi: 10.2196/resprot.9927. PMID: 29891466 Free PMC article. View publication

Atraumatic (pencil-point) versus conventional needles for lumbar puncture: a clinical practice guideline.

Rochwerg B, Almenawer SA, Siemieniuk RAC, Vandvik PO, Agoritsas T, Lytvyn L, Alhazzani W, Archambault P, D'Aragon F, Farhoumand PD, Guyatt G, Laake JH, Beltrán-Arroyave C, McCredie V, Price A, Chabot C, Zervakis T, Badhiwala J, St-Onge M, Szczeklik W, Møller MH, Lamontagne F. BMJ. 2018 May 22;361:k1920. doi: 10.1136/bmj.k1920. PMID: 29789372 Free PMC article. No abstract available. View publication

Do clinicians want recommendations? A multicenter study comparing evidence summaries with and without GRADE recommendations.

Neumann I, Alonso-Coello P, Vandvik PO, Agoritsas T, Mas G, Akl EA, Brignardello-Petersen R, Emparanza J, McCullagh L, De Sitio C, McGinn T, Almodaimegh H, Almodaimegh K, Rivera S, Rojas L, Stirnemann J, Irani J, Hlais S, Mustafa R, Bdair F, Aly A, Kristiansen A, Izcovich A, Ramirez A, Brozek J, Guyatt G, Schünemann HJ. J Clin Epidemiol. 2018 Jul;99:33-40. doi: 10.1016/j.jclinepi.2018.02.026. Epub 2018 Mar 9. PMID: 29530644 View publication

Systematic reviews do not adequately report or address missing outcome data in their analyses: a methodological survey.

Kahale LA, Diab B, Brignardello-Petersen R, Agarwal A, Mustafa RA, Kwong J, Neumann I, Li L, Lopes LC, Briel M, Busse JW, Iorio A, Vandvik PO, Alexander PE, Guyatt G, Akl EA. J Clin Epidemiol. 2018 Jul;99:14-23. doi: 10.1016/j.jclinepi.2018.02.016. Epub 2018 Mar 2. PMID: 29505859 Review. View publication

Do we have trustworthy guidelines for clinical practice in Norway?

Vandvik PO. Tidsskr Nor Laegeforen. 2018 Feb 19;138(4). doi: 10.4045/tidsskr.18.0102. Print 2018 Feb 20. PMID: 29460572 English, Norwegian. No abstract available. View publication

2017

Early vasopressor use following traumatic injury: a systematic review.

Hylands M, Toma A, Beaudoin N, Frenette AJ, D'Aragon F, Belley-Côté É, Charbonney E, Møller MH, Laake JH, Vandvik PO, Siemieniuk RA, Rochwerg B, Lauzier F, Green RS, Ball I, Scales D, Murthy S, Kwong JSW, Guyatt G, Rizoli S, Asfar P, Lamontagne F. BMJ Open. 2017 Nov 17;7(11):e017559. doi: 10.1136/bmjopen-2017-017559. PMID: 29151048 Free PMC article. Review. View publication

Corticosteroids for treatment of sore throat: systematic review and meta-analysis of randomised trials.

Sadeghirad B, Siemieniuk RAC, Brignardello-Petersen R, Papola D, Lytvyn L, Vandvik PO, Merglen A, Guyatt GH, Agoritsas T. BMJ. 2017 Sep 20;358:j3887. doi: 10.1136/bmj.j3887. PMID: 28931508 Free PMC article. Review. View publication

[New specialist training for physicians - from Swiss cheese to strongman?].

Bretthauer M, Vandvik PO, Skjeldestad FE, Frich JC, Lange T, Løberg M. Tidsskr Nor Laegeforen. 2017 Sep 18;137(17). doi: 10.4045/tidsskr.17.0637. Print 2017 Sep 19. PMID: 28925200 Norwegian. No abstract available. View publication

Values and preferences of women living with HIV who are pregnant, postpartum or considering pregnancy on choice of antiretroviral therapy during pregnancy.

Lytvyn L, Siemieniuk RA, Dilmitis S, Ion A, Chang Y, Bala MM, Manja V, Mirza R, Rodriguez-Gutierrez R, Mir H, El Dib R, Banfield L, Vandvik PO, Bewley S. BMJ Open. 2017 Sep 11;7(9):e019023. doi: 10.1136/bmjopen-2017-019023. PMID: 28893759 Free PMC article. Review. View publication

Antiretroviral therapy in pregnant women living with HIV: a clinical practice guideline.

Siemieniuk RAC, Lytvyn L, Mah Ming J, Mullen RM, Anam F, Otieno T, Guyatt GH, Taylor GP, Beltrán-Arroyave C, Okwen PM, Nduati R, Kinuthia J, Luma HN, Kirpalani H, Merglen A, Lesi OA, Vandvik PO, Agoritsas T, Bewley S. BMJ. 2017 Sep 11;358:j3961. doi: 10.1136/bmj.j3961. PMID: 28893728 Free PMC article. View publication

Incretin based treatments and mortality in patients with type 2 diabetes: systematic review and meta-analysis.

Liu J, Li L, Deng K, Xu C, Busse JW, Vandvik PO, Li S, Guyatt GH, Sun X. BMJ. 2017 Jun 8;357:j2499. doi: 10.1136/bmj.j2499. PMID: 28596247 Free PMC article. Review. View publication

Status report from Norway: Implementation of patient involvement in Norwegian health care.

Kasper J, Lager AR, Rumpsfeld M, Kienlin S, Smestad KH, Bråthen T, Ankell H, Knutsen T, Kløvtveit R, Gulbrandsen P, Vandvik PO, Heen AF, Flottorp S, Tollåli G, Eiring Ø. Z Evid Fortbild Qual Gesundhwes. 2017 Jun;123-124:75-80. doi: 10.1016/j.zefq.2017.05.015. Epub 2017 May 22. PMID: 28546052 Review. View publication

A systematic review of vasopressor blood pressure targets in critically ill adults with hypotension.

Hylands M, Moller MH, Asfar P, Toma A, Frenette AJ, Beaudoin N, Belley-Côté É, D'Aragon F, Laake JH, Siemieniuk RA, Charbonney E, Lauzier F, Kwong J, Rochwerg B, Vandvik PO, Guyatt G, Lamontagne F. Can J Anaesth. 2017 Jul;64(7):703-715. doi: 10.1007/s12630-017-0877-1. Epub 2017 May 11. PMID: 28497426 Review. English. View publication

Guideline for opioid therapy and chronic noncancer pain.

Busse JW, Craigie S, Juurlink DN, Buckley DN, Wang L, Couban RJ, Agoritsas T, Akl EA, Carrasco-Labra A, Cooper L, Cull C, da Costa BR, Frank JW, Grant G, Iorio A, Persaud N, Stern S, Tugwell P, Vandvik PO, Guyatt GH. CMAJ. 2017 May 8;189(18):E659-E666. doi: 10.1503/cmaj.170363. PMID: 28483845 Free PMC article. No abstract available. View publication

Addition of Ezetimibe to statins for patients at high cardiovascular risk: Systematic review of patient-important outcomes.

Fei Y, Guyatt GH, Alexander PE, El Dib R, Siemieniuk RAC, Vandvik PO, Nunnally ME, Gomaa H, Morgan RL, Agarwal A, Zhang Y, Bhatnagar N, Spencer FA. J Eval Clin Pract. 2018 Feb;24(1):222-231. doi: 10.1111/jep.12663. Epub 2017 Jan 16. PMID: 28090731 Review. View publication

Multilayered and digitally structured presentation formats of trustworthy recommendations: a combined survey and randomised trial

Brandt L, Vandvik PO, Alonso-Coello P, Akl EA, Thornton J, Rigau D, Adams K, O'Connor P, Guyatt G, Kristiansen A. BMJ Open. 2017 Feb 10;7(2):e011569. doi: 10.1136/bmjopen-2016-011569. PMID: 28188149; PMCID: PMC5306518. View publication

2016

Improving GRADE evidence tables part 1: a randomized trial shows improved understanding of content in summary of findings tables with a new format

Carrasco-Labra A, Brignardello-Petersen R, Santesso N, Neumann I, Mustafa RA, Mbuagbaw L, Etxeandia Ikobaltzeta I, De Stio C, McCullagh LJ, Alonso-Coello P, Meerpohl JJ, Vandvik PO, Brozek JL, Akl EA, Bossuyt P, Churchill R, Glenton C, Rosenbaum S, Tugwell P, Welch V, Garner P, Guyatt G, Schünemann HJ. J Clin Epidemiol. 2016 Jun;74:7-18. doi: 10.1016/j.jclinepi.2015.12.007. Epub 2016 Jan 11. PMID: 26791430. View publication

Do clinicians understand the size of treatment effects? A randomized survey across 8 countries

Johnston BC, Alonso-Coello P, Friedrich JO, Mustafa RA, Tikkinen KAO, Neumann I, Vandvik PO, Akl EA, da Costa BR, Adhikari NK, Dalmau GM, Kosunen E, Mustonen J, Crawford MW, Thabane L, Guyatt GH. CMAJ. 2016 Jan 5;188(1):25-32. doi: 10.1503/cmaj.150430. Epub 2015 Oct 26. PMID: 26504102; PMCID: PMC4695351. View publication

Compression Stockings for Preventing the Postthrombotic Syndrome in Patients with Deep Vein Thrombosis

Berntsen CF, Kristiansen A, Akl EA, Sandset PM, Jacobsen EM, Guyatt G, Vandvik PO. Am J Med. 2016 Apr;129(4):447.e1-447.e20. doi: 10.1016/j.amjmed.2015.11.031. Epub 2015 Dec 31. PMID: 26747198. View publication

Patient values and preferences on transcatheter or surgical aortic valve replacement therapy for aortic stenosis: a systematic review

Lytvyn L, Guyatt GH, Manja V, Siemieniuk RA, Zhang Y, Agoritsas T, Vandvik PO. BMJ Open. 2016 Sep 29;6(9):e014327. doi: 10.1136/bmjopen-2016-014327. PMID: 27687903; PMCID: PMC5051506. View publication

Agreements between Industry and Academia on Publication Rights: A Retrospective Study of Protocols and Publications of Randomized Clinical Trials

Kasenda B, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Ebrahim S, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. PLoS Med. 2016 Jun 28;13(6):e1002046. doi: 10.1371/journal.pmed.1002046. PMID: 27352244; PMCID: PMC4924795. View publication

GRADE Working Group. GRADE Evidence to Decision (EtD) frameworks: a systematic and transparent approach to making well informed healthcare choices. 2: Clinical practice guidelines

Alonso-Coello P, Oxman AD, Moberg J, Brignardello-Petersen R, Akl EA, Davoli M, Treweek S, Mustafa RA, Vandvik PO, Meerpohl J, Guyatt GH, Schünemann HJ; BMJ. 2016 Jun 30;353:i2089. doi: 10.1136/bmj.i2089. PMID: 27365494. View publication

Prognosis after surgical replacement with a bioprosthetic aortic valve in patients with severe symptomatic aortic stenosis: systematic review of observational studies

Foroutan F, Guyatt GH, O'Brien K, Bain E, Stein M, Bhagra S, Sit D, Kamran R, Chang Y, Devji T, Mir H, Manja V, Schofield T, Siemieniuk RA, Agoritsas T, Bagur R, Otto CM, Vandvik PO. BMJ. 2016 Sep 28;354:i5065. doi: 10.1136/bmj.i5065. PMID: 27683072; PMCID: PMC5040922. View publication

Tailoring implementation strategies for evidence-based recommendations using computerised clinical decision support systems: protocol for the development of the GUIDES tools

Van de Velde S, Roshanov P, Kortteisto T, Kunnamo I, Aertgeerts B, Vandvik PO, Flottorp S. Implement Sci. 2016 Mar 5;11:29. doi: 10.1186/s13012-016-0393-7. PMID: 26946141; PMCID: PMC4779557. View publication

Aspiration thrombectomy prior to percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis

El Dib R, Spencer FA, Suzumura EA, Gomaa H, Kwong J, Guyatt GH, Vandvik PO. BMC Cardiovasc Disord. 2016 Jun 2;16:121. doi: 10.1186/s12872-016-0285-4. Erratum in: BMC Cardiovasc Disord. 2016;16(1):182. PMID: 27255331; PMCID: PMC4890469. View publication

Authors seldom report the most patient-important outcomes and absolute effect measures in systematic review abstracts

Agarwal A, Johnston BC, Vernooij RW, Carrasco-Labra A, Brignardello-Petersen R, Neumann I, Akl EA, Sun X, Briel M, Busse JW, Ebrahim S, Granados CE, Iorio A, Irfan A, Martínez García L, Mustafa RA, Ramirez-Morera A, Selva A, Solà I, Sanabrai AJ, Tikkinen KA, Vandvik PO, Zhang Y, Zazueta OE, Zhou Q, Schunemann HJ, Guyatt GH, Alonso-Coello P. J Clin Epidemiol. 2017 Jan;81:3-12. doi: 10.1016/j.jclinepi.2016.08.004. Epub 2016 Aug 21. PMID: 27555080. View publication

Scandinavian clinical practice guideline on fluid and drug therapy in adults with acute respiratory distress syndrome

Claesson J, Freundlich M, Gunnarsson I, Laake JH, Møller MH, Vandvik PO, Varpula T, Aasmundstad TA. Acta Anaesthesiol Scand. 2016 Jul;60(6):697-709. doi: 10.1111/aas.12713. Epub 2016 Mar 14. PMID: 26988416; PMCID: PMC6680148. View publication

Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study

Schandelmaier S, von Elm E, You JJ, Blümle A, Tomonaga Y, Lamontagne F, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Bassler D, Busse JW, Ferreira-González I, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Cook DJ, Meade MO, Bucher HC, Kasenda B, Briel M. Crit Care Med. 2016 Jan;44(1):130-7. doi: 10.1097/CCM.0000000000001369. PMID: 26468895. View publication

Systematic reviews experience major limitations in reporting absolute effects

Alonso-Coello P, Carrasco-Labra A, Brignardello-Petersen R, Neumann I, Akl EA, Vernooij RW, Johnston BC, Sun X, Briel M, Busse JW, Ebrahim S, Granados CE, Iorio A, Irfan A, Martínez García L, Mustafa RA, Ramírez-Morera A, Selva A, Solà I, Sanabria AJ, Tikkinen KA, Vandvik PO, Zazueta OE, Zhang Y, Zhou Q, Schünemann H, Guyatt GH. J Clin Epidemiol. 2016 Apr;72:16-26. doi: 10.1016/j.jclinepi.2015.11.002. Epub 2015 Nov 10. PMID: 26560992. View publication

Meta-analysis of antibiotics versus appendicectomy for non-perforated acute appendicitis

Sallinen V, Akl EA, You JJ, Agarwal A, Shoucair S, Vandvik PO, Agoritsas T, Heels-Ansdell D, Guyatt GH, Tikkinen KA. Br J Surg. 2016 May;103(6):656-667. doi: 10.1002/bjs.10147. Epub 2016 Mar 17. PMID: 26990957; PMCID: PMC5069642. View publication

Introduction to BMJ Rapid Recommendations

Siemieniuk RA, Agoritsas T, Macdonald H, Guyatt GH, Brandt L, Vandvik PO. BMJ. 2016 Sep 28;354:i5191. doi: 10.1136/bmj.i5191. PMID: 27680768. View publication

Review: In severe aortic stenosis, TAVI and conventional surgery do not differ for ≤ 30-day or ≤ 1-year mortality

Vandvik PO, Guyatt G. Ann Intern Med. 2016 Sep 20;165(6):JC31. doi: 10.7326/ACPJC-2016-165-6-031. PMID: 27653728. View publication

Erratum to: Aspiration thrombectomy prior to percutaneous coronary intervention in ST-elevation myocardial infarction: a systematic review and meta-analysis

El Dib R, Spencer FA, Suzumura EA, Gomaa H, Kwong J, Guyatt GH, Vandvik PO. BMC Cardiovasc Disord. 2016 Sep 20;16(1):182. doi: 10.1186/s12872-016-0332-1. Erratum for: BMC Cardiovasc Disord. 2016 Jun 02;16:121. PMID: 27650912; PMCID: PMC5028941. View publication

Planning and reporting of quality-of-life outcomes in cancer trials

Schandelmaier S, Conen K, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M, Kasenda B; DISCO study group. Ann Oncol. 2016 Jan;27(1):209. doi: 10.1093/annonc/mdv559. Epub 2015 Nov 25. Erratum for: Ann Oncol. 2015 Sep;26(9):1966-73. PMID: 26612098; PMCID: PMC5266092. View publication

Living cumulative network meta-analysis to reduce waste in research: A paradigmatic shift for systematic reviews?

Vandvik PO, Brignardello-Petersen R, Guyatt GH. BMC Med. 2016 Mar 29;14:59. doi: 10.1186/s12916-016-0596-4. PMID: 27025849; PMCID: PMC4812628. View publication

2015

Decision aids that really promote shared decision making: the pace quickens

Agoritsas T, Heen AF, Brandt L, Alonso-Coello P, Kristiansen A, Akl EA, Neumann I, Tikkinen KA, Weijden Tv, Elwyn G, Montori VM, Guyatt GH, Vandvik PO. BMJ. 2015 Feb 10;350:g7624. doi: 10.1136/bmj.g7624. PMID: 25670178; PMCID: PMC4707568. View publication

Use of GRADE for assessment of evidence about prognosis: rating confidence in estimates of event rates in broad categories of patients

Iorio A, Spencer FA, Falavigna M, Alba C, Lang E, Burnand B, McGinn T, Hayden J, Williams K, Shea B, Wolff R, Kujpers T, Perel P, Vandvik PO, Glasziou P, Schunemann H, Guyatt G. BMJ. 2015 Mar 16;350:h870. doi: 10.1136/bmj.h870. PMID: 25775931. View publication

Enabling Living Systematic Reviews and Clinical Guidelines Through Semantic Technologies

Slaughter, Laura; Berntsen, Christopher Friis; Brandt, Linn; Mavergames, Chris. D-Lib Magazine 2015 (1082-9873) Vol. 21 (1-2). View publication

Development of a novel, multilayered presentation format for clinical practice guidelines

Kristiansen A, Brandt L, Alonso-Coello P, Agoritsas T, Akl EA, Conboy T, Elbarbary M, Ferwana M, Medani W, Murad MH, Rigau D, Rosenbaum S, Spencer FA, Treweek S, Guyatt G, Vandvik PO. Chest. 2015 Mar;147(3):754-763. doi: 10.1378/chest.14-1366. PMID: 25317597. View publication

2014

Applying new strategies for the national adaptation, updating, and dissemination of trustworthy guidelines: results from the Norwegian adaptation of the Antithrombotic Therapy and the Prevention of Thrombosis, 9th Ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines

Kristiansen A, Brandt L, Agoritsas T, Akl EA, Berge E, Flem Jacobsen A, Granan LP, Halvorsen S, Guyatt G, Vandvik PO. Chest. 2014 Sep;146(3):735-761. doi: 10.1378/chest.13-2993. PMID: 25180724. View publication

Implementation of transcatheter aortic valve insertion (TAVI) in clinical practice: An ethical analysis

Ohldieck, Annabel Eide; Nordrehaug, Jan Erik; Vandvik, Per Olav; Schaufel, Margrethe Aase; Norheim, Ole Frithjof. Clinical Ethics 2014 (1477-7509) Vol. 9 (2), s. 96-103 View publication

Adaptation of trustworthy guidelines developed using the GRADE methodology: a novel five-step process

Kristiansen A, Brandt L, Agoritsas T, Akl EA, Berge E, Bondi J, Dahm AE, Granan LP, Halvorsen S, Holme PA, Flem Jacobsen A, Jacobsen EM, Neumann I, Sandset PM, Sætre T, Tveit A, Vartdal T, Guyatt G, Vandvik PO. Chest. 2014 Sep;146(3):727-734. doi: 10.1378/chest.13-2828. PMID: 25180723. View publication

Una nueva generación de guías de práctica clínica confiables a través de MAGIC [A new generation of reliable clinical practice guidelines through MAGIC]

Olav Vandvik P, Fog Heen A, Brandt L. Rev Peru Med Exp Salud Publica. 2014;31(1):118-26. Spanish. PMID: 24718536. View publication

Effectiveness of computerized decision support systems linked to electronic health records: a systematic review and meta-analysis

Moja L, Kwag KH, Lytras T, Bertizzolo L, Brandt L, Pecoraro V, Rigon G, Vaona A, Ruggiero F, Mangia M, Iorio A, Kunnamo I, Bonovas S. Am J Public Health. 2014 Dec;104(12):e12-22. doi: 10.2105/AJPH.2014.302164. Epub 2014 Oct 16. PMID: 25322302; PMCID: PMC4232126. View publication

#CochraneTech: technology and the future of systematic reviews

Elliott J, Sim I, Thomas J, Owens N, Dooley G, Riis J, Wallace B, Thomas J, Noel-Storr A, Rada G, Struthers C, Howe T, MacLehose H, Brandt L, Kunnamo I, Mavergames C. Cochrane Database Syst Rev. 2014;(9):ED000091. doi: 10.1002/14651858.ED000091. PMID: 25288182. View publication

Nye retningslinjer for antitrombotisk behandling og tromboseprofylakse [New guidelines for antithrombotic therapy and thromboprophylaxis]

Kristiansen A, Brandt L, Berge E, Dahm AE, Halvorsen S, Sandset PM, Vandvik PO. Tidsskr Nor Laegeforen. 2014 May 13;134(9):921-2. Norwegian. doi: 10.4045/tidsskr.13.1582. PMID: 24828713. View publication

2013

Developing and Evaluating Communication Strategies to Support Informed Decisions and Practice Based on Evidence (DECIDE): protocol and preliminary results

Treweek S, Oxman AD, Alderson P, Bossuyt PM, Brandt L, Brożek J, Davoli M, Flottorp S, Harbour R, Hill S, Liberati A, Liira H, Schünemann HJ, Rosenbaum S, Thornton J, Vandvik PO, Alonso-Coello P; DECIDE Consortium. Implement Sci. 2013 Jan 9;8:6. doi: 10.1186/1748-5908-8-6. PMID: 23302501; PMCID: PMC3553065. View publication

Creating clinical practice guidelines we can trust, use, and share: a new era is imminent

Vandvik PO, Brandt L, Alonso-Coello P, Treweek S, Akl EA, Kristiansen A, Fog-Heen A, Agoritsas T, Montori VM, Guyatt G. Chest. 2013 Aug;144(2):381-389. doi: 10.1378/chest.13-0746. PMID: 23918106. View publication

Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design

Prutsky GJ, Domecq JP, Erwin PJ, Briel M, Montori VM, Akl EA, Meerpohl JJ, Bassler D, Schandelmaier S, Walter SD, Zhou Q, Coello PA, Moja L, Walter M, Thorlund K, Glasziou P, Kunz R, Ferreira-Gonzalez I, Busse J, Sun X, Kristiansen A, Kasenda B, Qasim-Agha O, Pagano G, Pardo-Hernandez H, Urrutia G, Murad MH, Guyatt G. Trials. 2013 Oct 16;14:335. doi: 10.1186/1745-6215-14-335. PMID: 24131702; PMCID: PMC3874848. View publication

2012

Formatting modifications in GRADE evidence profiles improved guideline panelists comprehension and accessibility to information. A randomized trial.

Vandvik PO, Santesso N, Akl EA, You J, Mulla S, Spencer FA, Johnston BC, Brozek J, Kreis J, Brandt L, Zhou Q, Schünemann HJ, Guyatt G. J Clin Epidemiol. 2012 Jul;65(7):748-55. doi: 10.1016/j.jclinepi.2011.11.013. Epub 2012 May 5. PMID: 22564503. View publication